Internship and thesis proposals
Development and Study of Ultrasound-Sensitive Microfluidic Droplets for Controlled Release of Active Compounds

Domaines
Biophysics
Physics of liquids
Hydrodynamics/Turbulence/Fluid mechanics
Metrology

Type of internship
Expérimental
Description
An interdisciplinary project at the interface of physics, microfluidics, and biomedical imaging. Context Microfluidic droplets are ideal micro-systems for encapsulating and controllably releasing active compounds such as drugs, chemical agents, or fragrances. The use of ultrasound waves allows for non- invasive, localized, and tunable triggering of this release. This internship is part of an interdisciplinary project at the interface of physics, microfluidics, and acoustics, aiming to understand and optimize the physical mechanisms governing ultrasound–droplet interactions. Internship Objectives: • Develop protocols for droplet production and characterization (size, stability, etc.). • Study the effects of ultrasound on these droplets: release, deformation, fragmentation. • Optimize ultrasonic parameters (frequency, power, duration) for precise release control. • Quantify the kinetics of active compound release. • Analyze experimental data and model results using Python scripts. • Present results and contribute to the writing of a report or scientific article.

Contact
Nicolas Taulier
0602480237


Email
Laboratory : Laboratoire d’Imagerie Biomédicale Sorbonne Université - CNRS UMR 7371
Team : Médecine et Ultrasons (MU)
Team Website
/ Thesis :    Funding :