The periosteum is a soft tissue that covers all the bones in the body. It nourishes the cortical bone, protects it from fractures, and transmits forces from tendons and ligaments. Located at the interface between bone and soft tissue, the periosteum transmits mechanical stimuli between these two environments, thereby influencing bone cell differentiation, remodeling, and healing. However, the role of periosteal adhesion in transmitting these stimuli remains poorly understood. The objective of this internship—and subsequent thesis—is to thoroughly characterize the adhesion properties of the periosteum and to achieve a deeper understanding of the underlying mechanisms, particularly at the microstructural level. This will be accomplished through biomechanical experiments, primarily instrumented peeling tests to detach the periosteum from the bone.