Domaines
Biophysics
Soft matter
Physics of liquids
Physics of living systems
Hydrodynamics/Turbulence/Fluid mechanics
Type of internship
Expérimental et théorique Description
Metastasis remains the leading cause of cancer-related deaths. A critical step in metastasis involves circulating tumor cells (CTCs) moving through confined environment of the vascular microcirculation before colonizing distant tissues. Unlike rigid tubes, these vessels are soft and deformable, continuously reshaping under pressure and flow. A critical yet often overlooked aspect here is how fluid flow locally deforms the vascular network, and how these deformations in turn alter the flow itself. Capturing this two-way feedback is essential to understanding the physics of transport in living systems- insights that goes well beyond cancer metastasis.
Contact
Martin Brandenbourger